Metatron 4025 Hunter will be an important approach to lung disease(2)
For patients with suspected DILD, the power of routine X-ray examination appears to be limited because the sensitivity and specificity of this method have proven to be inefficient. Data from 458 patients with histologically confirmed DILD were studied. In 10% of cases, chest X-ray findings turned out to be normal. Of the 86 patients affected by DILD, no pathological changes were detected in 50% of patients with histologically confirmed bronchiectasis and more than 20% of patients with radiographically demonstrated emphysema. Radiographs are also likely to reveal false-positive findings from investigations. We found that in 10-20% of patients with X-ray-confirmed signs of DILD, no changes were detected during lung biopsy.
Computer nonlinear diagnostics (NLS) using the metatron 4025 Hunter is one of the promising methods for diagnosing lung diseases today. NLS significantly improves the communication of fine morphological elements in lung tissue and opens up new opportunities to identify interstitial diseases of the bronchoalveolar system. NLS has high sensitivity in detecting interstitial lesions in parenchymal and small nodules.
The findings demonstrate that NLS has better sensitivity in detecting acute and chronic diffuse lung disease. The sensitivity of NLS diagnostics to detect lung disease is 85% compared to 70% for chest X-rays.
The accumulated experience also provides additional rationale for asserting that NLS is an efficient method for diagnosing various diffuse lung diseases, including DILD, and is superior to "classical" chest radiography in terms of sensitivity.
It should be noted that the high sensitivity of the NLS method was achieved without sacrificing the specificity and diagnostic accuracy of the method. Among patients affected by DILD, NLS specificity was 86% compared with 76% by radiography. In particular, the high sensitivity (86-88%) and specificity (83-89%) of NLS were demonstrated in the diagnosis of bronchiectasis.
Even with evidence of certain clinical symptoms, the diagnostic accuracy of classical radiography in patients affected by DILD appears to be limited. The reason is both the superposition of the images in the X-ray and the low contrast of the tiny lung structures.
NLS does not have these aspects, which is why it is considered a more effective method for identifying diffuse lesions in lung tissue compared to radiography and traditional computed tomography.
In addition, the NLS method has higher sensitivity, specificity, and diagnostic accuracy and can be a determinant for assessing the activity of the pathological process in DILD patients. In some cases, NLS can be used not only to define the presence or absence of pathology
The growing impact of metatron 4025 Hunter on various diseases