NLS-Diagnosis Of Prostate Diseases By Metatron 4025 Hunter

NLS-Diagnosis Of Prostate Diseases By Metatron 4025 Hunter

An ever growing number of physicians enjoy an opportunity of a screening NLS diacrisis of prostate grand and urinary bladder. In the West prostate cancer makes 20% of the total cancer diseases and ranks second to lung tumors as a death cause.

According to some autopsy findings with a histological investigation of the prostate, 12- 47% of men aged over 50 appeared to have cancerous nidi. Clinically, cancer is diagnosed more rarely because a high percentage of that number corresponds to ‘minor forms’ of cancer that have low invasiveness, so the patients suffering from it die of another kind of pathology.

To enhance the quality of prostate diseases diagnosis it is important to comprehend the specifics of topographic and zonal anatomy of a particular organ.

The prostate gland is located in the small pelvis between the bladder and anterior abdominal wall, anterior rectum wall and secondary urogenital diaphragm. The gland has a chestnut shape and tightly envelops the bladder cervix and prostate urethra. The gland base is lightly connected with the bladder into a coherent mass. Its anterior surface is directed to the symphysis, and the posterior one – to the rectum ampulla. The posterior surface of the gland has an expressed sulcus, which enables to conventionally subdivide the gland into the left and right lobes. Besides, there is a protruding middle cone-shaped lobe confirmed anteriorly by the prostatic urethra and by the spermatic ducts posteriorly.

According to zonal anatomy theory usually 4 glandular zones are distinguished in the prostate. The correct interpretation of NLS data largely depends on the knowledge of their topical pattern. 20% of the glandular tissue correspond to the central zone (CZ). The peripheral zone (PZ) occupies 75%. The intermediate (transitory) zones (TZ) make up 5% of the total amount of the glandular tissue.

If any pathological changes are detected in the NLS-graph it is recommended to:

- specify their exact location;

- perform histography of the pathological area and area of the tissue with a normal structure.

It will be helpful for the case follow-ups. At a benign hyperplasia NLS enables detection of the direction of the principal germination. In case of hyper-trophic transitory zones the gland proliferates inwards. Though darkened lateral zones are formed (4-5 points on Flandler’s scale), the nodes can still be always visualized.  The trans-rectal NLS offers the most detailed and authentic information.

As can be seen from NLS-investigation, chronic prostatitis does not give a common characteristic picture, however the morphological processes in different phases of the disease are reflected in histograms. With a long-lasting disease the chromogenic density tends to rise due to a post-inflammatory substitution for the glandular component and its histograms. In the ‘organ preparations’ mode destructuring of the fibrous component starts to predominate.

Analysis of histograms of the nidi help differentiate an onco-process. The method’s sensitivity becomes higher with both ‘elimination’ and ‘NLS-analysis’ modes in use. Peripheral zones have first place as far as cancer incidence rate is concerned. They constitute 70-80% of cases. Transitory zones (TZ) are affected in 10-20% and CZ in less than 5% of cases. In transitory zones a tumor nidus should be looked for within 3-4 mm from the capsule. In case of an oncological alertness the symmetry in the lobe affection is assessed with respect to the sagittal axis and intensity of the black patch (4-5 points on Flandler’s scale), in the adjacent organs, especially seminal vesicles and bladder because in 25% of cases metastases occurs through the gland apex and seminiferous tracts.

Considering the fact that cancer often develops with some diffuse changes occurring in the background, for example, with chronic prostatitis or adenomatosis, it is not always possible to visualize newly formed cancerous areas. In such cases the results of PSA level definition and digital rectal examination should be considered. The PSA level is defined considering the patient’s age and gland volume.

NLS-method by Metatron 4025 Hunter enables diagnosis of most prostate diseases and being a screening diagnosis method, it should be supplemented by biopsy, should any pathological changes be detected.

The final diagnosis should be made on the basis of the clinic lab data and the results of digital rectal examination in combination with biopsy only.