Biophilia Tracker for Oncology Urology
Today, urology is an area where 3D NLS imaging methods can also be widely applied. However, until today, the application of 3D NLS methods in clinical practice would revolutionize our perspective on this issue. We believe that this problem is actually local because the majority of surgical patients underwent invasive transurethral resection.
Application of 3D NLS studies with spectral entropy analysis by Biophilia Tracker, performed during surgical incision, allowed us to detect additional neoplastic tumors not documented by 2D NLS studies in 37% of patients. The application of a three-dimensional approach made it possible to determine the extent of the tumor's local spreading process; control the depth of resection of the bladder wall; and reduce the risk of complications during incision.
Usually, the diagnosis and morphological verification of rectal cancer do not present difficulties. However, it is not always possible to assess the extent of organ wall invasion using standard diagnostic methods. Traditional two-dimensional NLS studies have been widely used as a diagnostic method for recurrent rectal cancer after organ removal. However, initial diagnosis of disease using 2D NLS imaging has been hampered for several reasons. First, given that the rectum is only partially visible (80% of the entire organ surface area) in 2D NLS scans.
The application of three-dimensional NLS imaging allows accurate differentiation of all layers of the rectal wall to diagnose the depth of tumor invasion and determine the stage of the disease using spectral entropy analysis. This method helps detect nodal changes greater than 1.5 mm in metastatic disease in the perirectal lymph nodes. During preoperative radiotherapy monitoring, 3D NLS imaging helps to accurately detect tumor size reduction; identify structural changes associated with medical morbidity; and determine reduction of tumor infiltration in para-rectal tissues. Therefore, three-dimensional NLS imaging can be considered as a method for the initial diagnosis of rectal cancer. It enables physicians to address the most important diagnostic questions related to identifying the length of the tumor process, the degree of local tumor spread and monitoring the efficiency of preoperative treatments. In organ preservation surgery, three-dimensional NLS imaging can be used as an effective method for early diagnosis of recurrent tumors in the anastomotic area.
In conclusion, in terms of modern Biophilia Tracker features, we would like to emphasize that this method can effectively meet the goals of detection of tumor changes, determination of disease staging and qualitative assessment of treatment.